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Trismus is defined as painful restriction in opening the mouth due to a muscle spasm, [5] however it can also refer to limited mouth opening of any cause. [6] Another definition of trismus is simply a limitation of movement. [4] Historically and commonly, the term lockjaw was sometimes used as a synonym for both trismus [2] and tetanus. [7]
Tetanus (from Ancient Greek τέτανος ' tension, stretched, rigid '), also known as lockjaw, is a bacterial infection caused by Clostridium tetani and characterized by muscle spasms. In the most common type, the spasms begin in the jaw and then progress to the rest of the body.
6.5 years = 2,374 days and 56,976 hours, or 3,418,560 minutes. 5,772 cigarettes per year for 54 years = 311,688 cigarettes. 3,418,560/311,688=11 minutes per cigarette.
The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...
A National Institute on Drug Abuse video entitled Anyone Can Become Addicted to Drugs. [21]Nicotine dependence is defined as a neurobiological adaptation to repeated drug exposure that is manifested by highly controlled or compulsive use, the development of tolerance, experiencing withdrawal symptoms upon cessation including cravings, and an inability to quit despite harmful effects. [9]
Nicotine is an addictive substance found most commonly in tobacco and tobacco products including cigarettes, cigars, chewing tobacco, e-cigarette liquid, pipe tobacco, snus, snuff, and nicotine medications such as nicotine gum. Withdrawal is the body’s reaction to not having the nicotine it had become accustomed to.
Cigarette smoking for weight loss is a weight control method whereby one consumes tobacco, often in the form of cigarettes, to decrease one's appetite. The practice dates to early knowledge of nicotine as an appetite suppressant. Tobacco smoking was associated with appetite suppression among Pre-Columbian indigenous Americans and Old World ...
A 2015 review concluded that "Nicotine acts as a gateway drug on the brain, and this effect is likely to occur whether the exposure is from smoking tobacco, passive tobacco smoke or e-cigarettes." [25] Nicotine may have a profound impact on sleep. [26] The effects on sleep vary after being intoxicated, during withdrawal, and from long-term use ...