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Cross-species transmission is the most significant cause of disease emergence in humans and other species. [citation needed] Wildlife zoonotic diseases of microbial origin are also the most common group of human emerging diseases, and CST between wildlife and livestock has appreciable economic impacts in agriculture by reducing livestock productivity and imposing export restrictions. [2]
Initially identified as a central figure labeled "Patient Zero", Dugas faced allegations of being a primary source of HIV transmission to the United States. This narrative, popularized notably by Randy Shilts ' 1987 book And the Band Played On , has been refuted through subsequent scientific scrutiny and historical re-evaluation.
As of 2016, it is estimated that there are 1.5 million adults and children living with HIV/AIDS in North America, excluding Central America and the Caribbean. [ 1 ] 70,000 adults and children are newly infected every year, and the overall adult prevalence [ clarification needed ] is 0.5%.
HIV-1 is most similar to the SIV found in common chimpanzees (SIVcpz) in southeastern Cameroon, giving rise to the notion that HIV-1 emerged from chimpanzees in this area. [4] SIVcpz itself emerged in chimpanzees as the result of a recombination of two separate lineages of SIV known to infect red-capped mangabey , and Cercopithecus species.
Proponents of this dating link the HIV epidemic with the emergence of colonialism and growth of large colonial African cities, leading to social changes, including a higher degree of non-monogamous sexual activity, the spread of prostitution, and the concomitant high frequency of genital ulcer diseases (such as syphilis) in nascent colonial cities.
Robert Lee Rayford [1] (February 3, 1953 – May 15, 1969), [2] sometimes identified as Robert R. due to his age, was an American teenager from Missouri who has been suggested to represent the earliest confirmed case of HIV/AIDS in North America. This is based on evidence published in 1988 in which the authors claimed that medical evidence ...
Spillover: Animal Infections and the Next Human Pandemic is 2012 non-fiction book by David Quammen.The book, written in narrative form, tells through the personal experiences of the author, who interviewed numerous pathologists and virologists globally to trace the evolution of some of the major pathogens that have affected the human species following a species leap (), a natural process by ...
HIV is a retrovirus that primarily infects components of the human immune system such as CD4 + T cells, macrophages and dendritic cells. It directly and indirectly destroys CD4 + T cells. [88] HIV is a member of the genus Lentivirus, [89] part of the family Retroviridae. [90] Lentiviruses share many morphological and biological characteristics.
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