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Sepsis is defined as SIRS in response to an infectious process. [48] Severe sepsis is defined as sepsis with sepsis-induced organ dysfunction or tissue hypoperfusion (manifesting as hypotension, elevated lactate, or decreased urine output). Severe sepsis is an infectious disease state associated with multiple organ dysfunction syndrome (MODS) [9]
Septic shock is a result of a systemic response to infection or multiple infectious causes. The precipitating infections that may lead to septic shock if severe enough include but are not limited to appendicitis, pneumonia, bacteremia, diverticulitis, pyelonephritis, meningitis, pancreatitis, necrotizing fasciitis, MRSA and mesenteric ischemia.
[1] [2] It is one of four categories of shock, a condition where there is not enough oxygen-carrying blood to meet the metabolic needs of the cells which make up the body's tissues and organs. [2] Distributive shock is different from the other three categories of shock in that it occurs even though the output of the heart is at or above a ...
Begg says sepsis mortality in developed countries like the UK is about 15%, but warns that many surviving patients suffer from the consequences of sepsis, which can include amputated limbs, for ...
It is unclear why some people with the mentioned factors above do not develop ARDS and others do. [citation needed] Pneumonia and sepsis are the most common triggers, and pneumonia is present in up to 60% of patients and may be either causes or complications of ARDS. Alcohol excess appears to increase the risk of ARDS. [47]
[8] [9] The suggestion is that for a child being exposed to microbes early in life, taking fewer antibiotics, living in a large family, and growing up in the country stimulate the T H 1 response and reduce the odds of developing asthma. [10] Asthma is associated with a procoagulant state in the bronchoalveolar space. [11]
In some subjects, the constriction does not return to normal, and recurs after three to four hours, which may last up to a day or more. The first is named the early asthmatic response, and the latter the late asthmatic response. Bronchoconstriction can occur as a result of anaphylaxis, even when the allergen is not inhaled.
They are spiral-shaped mucus plugs from subepithelial mucous gland ducts of bronchi. They may occur in several different lung diseases [1] and may refer to parts of the desquamated epithelium seen in lavages from asthmatic patients. [2] These microscopic casts are named after German physician Heinrich Curschmann (1846-1910).