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Sotatercept, sold under the brand name Winrevair is a medication used for the treatment of pulmonary arterial hypertension. [6] It is an activin signaling inhibitor, [ 6 ] based on the extracellular domain of the activin type 2 receptor expressed as a recombinant fusion protein with immunoglobulin Fc domain (ACTRIIA-Fc). [ 9 ]
Winrevair, which costs around $238,000 annually, was the first treatment to secure approval from the U.S. Food and Drug Administration from a class of drugs, which target a type of protein called ...
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Research shows the drug increases bone formation and decreases bone resorption in postmenopausal women with low bone density. Romosozumab was approved for medical use in Japan, the United States and the European Union in 2019. [7] [10] [11] The US Food and Drug Administration (FDA) considers it to be a first-in-class medication. [12]
The therapy, branded Winrevair, is approved for treating pulmonary arterial hypertension (PAH), which affects about 40,000 people in the United States. US FDA approves Merck's therapy for rare ...
Treprostinil (Remodulin) was approved for use in the United States in May 2002, [1] [7] and again in July 2018. [10] Tyvaso, the inhaled form of treprostinil, was approved for use in the United States in July 2009. [11] Orenitram was approved in December 2013. [12] Treprostinil (Trepulmix) was approved for use in the European Union in April ...
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