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Hodgkin disease, chronic leukimia, lung cancer, polycythemia vera, T-cell lymphoma, mycosia fungoides Hepatotoxicity (rare) [18] Melphalan: IV, PO: Alkylates DNA. Malignant melanoma of the extremities, multiple myeloma, conditioning treatment before haemopoietic stem cell transplant.
The most common secondary neoplasm is secondary acute myeloid leukemia, which develops primarily after treatment with alkylating agents or topoisomerase inhibitors. [109] Survivors of childhood cancer are more than 13 times as likely to get a secondary neoplasm during the 30 years after treatment than the general population. [ 110 ]
Most commonly cancer treatment involves a series of separate therapies such as chemotherapy before surgery. [4] Angiogenesis inhibitors are sometimes used to enhance the effects of immunotherapies. [5] The choice of therapy depends upon the location and grade of the tumor and the stage of the disease, as well as the general state of the patient.
A neoplasm (/ ˈ n iː oʊ p l æ z əm, ˈ n iː ə-/) [1] [2] is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists in growing abnormally, even if the original trigger is ...
While uncommon in solid tumors, chromosomal translocations are a common cause of these diseases. This commonly leads to a different approach in diagnosis and treatment of hematological malignancies. Hematological malignancies are malignant neoplasms ("cancer"), and they are generally treated by specialists in hematology and/or oncology.
Cancers comprise a large family of diseases that involve abnormal cell growth with the potential to invade or spread to other parts of the body. [2] [7] They form a subset of neoplasms. A neoplasm or tumor is a group of cells that have undergone unregulated growth and will often form a mass or lump, but may be distributed diffusely. [27] [28]
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