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Antibiotic ointment is typically applied to the newborn's eyes within 1 hour of birth as prevention against gonococcal ophthalmia. [3] This may be erythromycin, tetracycline, or rarely silver nitrate [3] or Argyrol (mild silver protein). The use of 1-2% silver nitrate solution was introduced in 1881 by Credé as Credé's prophylaxis. [3] [12 ...
The US price of erythromycin rose three times between 2010 and 2015, from 24 cents per 500mg tablet in 2010 to $8.96 in 2015. [53] In 2017, a Kaiser Health News study found that the per-unit cost of dozens of generics doubled or even tripled from 2015 to 2016, increasing spending by the Medicaid program.
Credé prophylaxis is the practice of washing a newborn's eyes with a 2% silver nitrate solution to protect against neonatal conjunctivitis caused by Neisseria gonorrhoeae, thereby preventing blindness. [1] The Credé procedure was developed by the German physician Carl Siegmund Franz Credé who implemented it in his hospital in Leipzig in 1880 ...
Occasionally erythromycin ophthalmic ointment is recommended. [20] Other antibiotics, such as chloramphenicol or amoxicillin may also be used. [ 21 ] Chloramphenicol is used successfully in many parts of the world, but contains a black box warning in the United States due to concerns about aplastic anemia , which on rare occasions can be fatal.
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Figure 1.0 - Basic anatomical features of the human eye. Ophthalmic drug administration is the administration of a drug to the eyes, most typically as an eye drop formulation. Topical formulations are used to combat a multitude of diseased states of the eye. These states may include bacterial infections, eye injury, glaucoma, and dry eye. [1]
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