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They can be found at a depth of 900 µm in human fingertips. [4] In hairy skin, Merkel nerve endings are clustered into specialized epithelial structures called "touch domes" or "hair disks". Merkel receptors are also located in the mammary glands. Wherever they are found, the epithelium is arranged to optimize the transfer of pressure to the ...
Merkel cells, also known as Merkel–Ranvier cells or tactile epithelial cells, are oval-shaped mechanoreceptors essential for light touch sensation and found in the skin of vertebrates. They are abundant in highly sensitive skin like that of the fingertips in humans , and make synaptic contacts with somatosensory afferent nerve fibers .
A mechanoreceptor, also called mechanoceptor, is a sensory receptor that responds to mechanical pressure or distortion. Mechanoreceptors are located on sensory neurons that convert mechanical pressure into electrical signals that, in animals, are sent to the central nervous system.
Pallesthesia (\ˌpal-es-ˈthē-zh(ē-)ə\), or vibratory sensation, is the ability to perceive vibration. [1] [2] This sensation, often conducted through skin and bone, is usually generated by mechanoreceptors such as Pacinian corpuscles, Merkel disk receptors, and tactile corpuscles. [1]
Friedrich Sigmund Merkel (5 April 1845 – 28 May 1919) was a leading German anatomist and histopathologist of the late 19th century. In 1875, he provided the first full description of Tastzellen (touch cells), which occur in the skin of all vertebrates. [1] They were subsequently given the eponym "Merkel cells" in 1878 by Robert Bonnet (1851 ...
In humans, the cartilaginous bar of the mandibular arch is formed by what are known as Meckel's cartilages (right and left; also known as Meckelian cartilages), above which the incus and malleus are located. Meckel's cartilage arises from the first pharyngeal arch.
A free nerve ending (FNE) or bare nerve ending, is an unspecialized, afferent nerve fiber sending its signal to a sensory neuron. Afferent in this case means bringing information from the body's periphery toward the brain.
Tactile corpuscles or Meissner's corpuscles are a type of mechanoreceptor discovered by anatomist Georg Meissner (1829–1905) and Rudolf Wagner. [1] [2] This corpuscle is a type of nerve ending in the skin that is responsible for sensitivity to pressure.