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3586 16153 Ensembl ENSG00000136634 ENSMUSG00000016529 UniProt P22301 P18893 RefSeq (mRNA) NM_000572 NM_010548 RefSeq (protein) NP_000563 NP_034678 Location (UCSC) Chr 1: 206.77 – 206.77 Mb Chr 1: 130.95 – 130.95 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti- inflammatory cytokine ...
The IL-10 family is a family of interleukins. In addition to IL-10, it includes IL-19, IL-20, IL-22, IL-24 and IL-26. [1] Some sources also include the interferons IL-28 and IL-29. [2] The IL-10 family are helical cytokines categorized based on their specific similarities and can be classified as class 2 cytokines. [3]
Interleukin 10 (IL-10) is a protein that inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF, and GM-CSF produced by activated macrophages and by helper T cells. In structure, IL-10 is a protein of about 160 amino acids that contains four conserved cysteines involved in disulphide bonds. [ 33 ]
The Ilyushin Il-10 (Cyrillic Илью́шин Ил-10, NATO reporting name: "Beast" [3]) is a Soviet ground attack aircraft developed at the end of World War II by the Ilyushin construction bureau. It was also license -built in Czechoslovakia by Avia as the Avia B-33 .
Interleukin-10 receptor (IL-10R) is a type II cytokine receptor. The receptor is tetrameric , composed of 2 α [ 1 ] and 2 β [ 2 ] subunits. The α subunit (encoded in the Il10ra gene) is expressed on haematopoietic cells (such as T, B, NK, mast, and dendritic cells ) whilst the β subunit (encoded in the Il10rb gene ) is expressed ubiquitously.
B10 cells are presumed to originate from B10 progenitor (B10pro) cells, which can mature into B10eff cells with lipopolysaccharide (LPS) stimulation or CD40 litigation. [1] [8] In mice, B10eff cells (derived from B10 cells) actively secrete IL-10, whereas competency for IL-10 expression in B10pro cells must be induced by ex vivo stimulation. [1]
The standard definition of a reference range for a particular measurement is defined as the interval between which 95% of values of a reference population fall into, in such a way that 2.5% of the time a value will be less than the lower limit of this interval, and 2.5% of the time it will be larger than the upper limit of this interval, whatever the distribution of these values.
A reference range is usually defined as the set of values 95 percent of the normal population falls within (that is, 95% prediction interval). [2] It is determined by collecting data from vast numbers of laboratory tests.