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Research suggests that rhodiola rosea may reduce stress, as well as depression and anxiety symptoms. 5-HTP, also known as 5-hydroxytryptophan, has been found to increase serotonin levels in the brain.
In addition to curbing anxiety, a 2012 study suggests ashwagandha also lowers cortisol levels (the chemical released into your body when you’re stressed) and reduces insomnia.
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Limited clinical studies have found that supplementation with various ashwagandha extracts may decrease anxiety and perceived stress, and improve sleep. [ 3 ] [ 4 ] [ 16 ] As the studies used different extract preparations, durations of use, doses, and types of subjects, how ashwagandha may have effects in people remains undetermined, as of 2023.
Actoprotectors or synthetic adaptogens are compounds that enhance an organism's resilience to physical stress without increasing heat output. [1] Actoprotectors are distinct from other performance-enhancing substances in that they increase physical and psychological resilience via non-exhaustive action. [ 1 ]
The term "adaptogen" refers to non-toxic plants or their extracts purported to diminish stress and support overall wellbeing when consumed. [4] However, the definition of an adaptogen is vague and without adequate scientific evidence, making it impossible to determine what exactly makes a substance an adaptogen.
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