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  2. Diazepam - Wikipedia

    en.wikipedia.org/wiki/Diazepam

    Diazepam does not possess any chiral centers in its structure, but it does have two conformers.The two conformers mentioned were the 'P'-conformer and 'M'-conformer. Diazepam is an equimolar mixture and it was shown through CD spectra in serum protein solutions, that the 'P'-conformer is preferred by α1-acid glycoprotein b

  3. Benzodiazepine - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine

    Midazolam is the most commonly prescribed for this use because of its strong sedative actions and fast recovery time, as well as its water solubility, which reduces pain upon injection. Diazepam and lorazepam are sometimes used. Lorazepam has particularly marked amnesic properties that may make it more effective when amnesia is the desired effect.

  4. Effects of long-term benzodiazepine use - Wikipedia

    en.wikipedia.org/wiki/Effects_of_long-term...

    However, single very high doses of diazepam have been found to cause lifelong immunosuppression in neonatal rats. No studies have been done to assess the immunotoxic effects of diazepam in humans; however, high prescribed doses of diazepam, in humans, have been found to be a major risk of pneumonia, based on a study of people with tetanus.

  5. Sublingual administration - Wikipedia

    en.wikipedia.org/wiki/Sublingual_administration

    The method is limited by excessive salivation washing the chemical down the throat. Also, many alkaloids have an unpleasant taste which makes them difficult to hold in the mouth. Tablets of psychoactive pharmaceuticals usually include bitter chemicals such as denatonium in order to discourage abuse and also to discourage children from eating them.

  6. List of benzodiazepines - Wikipedia

    en.wikipedia.org/wiki/List_of_benzodiazepines

    The tables below contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses.

  7. Trip killer - Wikipedia

    en.wikipedia.org/wiki/Trip_killer

    A trip killer, or hallucinogen antidote, is a drug that aborts or reduces the effects of a hallucinogenic drug experience (or 'trip'). [1] [2] [3] [4] [5] As there ...

  8. Is your kid shy, or simply slow to warm up? Why being ... - AOL

    www.aol.com/lifestyle/kid-shy-simply-slow-warm...

    Often, children who are slow to warm up respond to seemingly minor changes in their environment with big reactions. They may refuse new activities or shadow their parent at a school function.

  9. Benzodiazepine overdose - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_overdose

    Benzodiazepine overdose (BZD OD) describes the ingestion of one of the drugs in the benzodiazepine class in quantities greater than are recommended or generally practiced. . The most common symptoms of overdose include central nervous system (CNS) depression, impaired balance, ataxia, and slurred spee