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Clindamycin has been proven to decrease the risk of premature births in women diagnosed with bacterial vaginosis during early pregnancy to about a third of the risk of untreated women. [ 39 ] The combination of clindamycin and quinine is the standard treatment for severe babesiosis .
Out of the many families of multidrug resistance pumps, lincosamides are most commonly shunted through pumps belonging to the resistance-nodulation-cell division superfamily. [17] Staphylococci express efflux pumps with specificity for 14 and 15 member ring macrolides and streptogramin B, but not lincosamide molecules.
It contains clindamycin, as the phosphate, a lincosamide antibacterial; adapalene, a synthetic retinoid; and benzoyl peroxide, an oxidizing agent. [2] It is applied to the skin . [ 2 ]
GBS-EOD manifests from 0 to 7 living days in the newborn, with most of the cases of EOD being apparent within 24 h from birth. GBS-LOD starts between 7 and 90 days after birth. [ 4 ] [ 12 ] [ 14 ] [ 22 ] Roughly 50% of newborns of GBS-colonized mothers are also GBS-colonized and (without prevention measures) 1-2% of these newborns will develop ...
Women should speak to their doctor or healthcare professional before starting or stopping any medications while pregnant. [1] Drugs taken in pregnancy including over-the counter-medications, prescription medications, nutritional supplements, recreational drugs, and illicit drugs may cause harm to the mother or the unborn child.
Clindamycin/benzoyl peroxide, sold under the brand name Benzaclin among others, is a topical gel used for the treatment of acne. [7] It is a fixed-dose combination of clindamycin , as the phosphate, an antibiotic ; and benzoyl peroxide , an antiseptic .
The WHO recommends avoiding ACT for women in their first trimester of pregnancy due to a lack of research on artemisinin's safety in early pregnancy. Instead the WHO recommends a seven-day course of clindamycin and quinine. [15] For pregnant women in their second or third trimesters, the WHO recommends a normal treatment course with an ACT. [16]
For those who do not improve after three days or who have severe disease, intravenous antibiotics should be used. [7] Globally, about 106 million cases of chlamydia and 106 million cases of gonorrhea occurred in 2008. [10] The number of cases of PID, however, is not clear. [8] It is estimated to affect about 1.5 percent of young women yearly. [8]