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  2. Chlordiazepoxide/clidinium bromide - Wikipedia

    en.wikipedia.org/wiki/Chlordiazepoxide/clidinium...

    Chlordiazepoxide is an anti-anxiety medication belonging to the benzodiazepine class. [4] Its use in IBS is thought to be due to its calming ability for patients that have IBS symptoms that are worsened by anxiety. Clidinium bromide is a synthetic quaternary ammonium antimuscarinic, [5] a sub-class of a family of drugs known as anticholinergics.

  3. Vortioxetine - Wikipedia

    en.wikipedia.org/wiki/Vortioxetine

    Vortioxetine was previously sold under the brand name Brintellix in the United States, but in May 2016, the US Food and Drug Administration (FDA) approved a name change to Trintellix in order to avoid confusion with the blood-thinning medication Brilinta . [57] [58] Other brand names include Torvox, Vantaxa, Voxigain, and Trivoxetin.

  4. Buprenorphine - Wikipedia

    en.wikipedia.org/wiki/Buprenorphine

    Buprenorphine, sold under the brand name Subutex among others, is an opioid used to treat opioid use disorder, acute pain, and chronic pain. [18] It can be used under the tongue (sublingual) , in the cheek (buccal) , by injection ( intravenous and subcutaneous ), as a skin patch (transdermal) , or as an implant .

  5. Effects of long-term benzodiazepine use - Wikipedia

    en.wikipedia.org/wiki/Effects_of_long-term...

    Although anxiety can temporarily increase as a withdrawal symptom, there is evidence that a reduction or withdrawal from benzodiazepines can lead to a reduction of anxiety symptoms in the long run. [4] [5] Due to these increasing physical and mental symptoms from long-term use of benzodiazepines, slow withdrawal is recommended for long-term users.

  6. Stress-related disorders - Wikipedia

    en.wikipedia.org/wiki/Stress-related_disorders

    This arises after response to a stressful event or situation of an exceptionally threatening nature and likely to cause pervasive distress (great pain, anxiety, sorrow, acute physical or mental suffering, affliction, trouble) in almost anyone.

  7. Development and discovery of SSRI drugs - Wikipedia

    en.wikipedia.org/wiki/Development_and_discovery...

    SSRIs prevent 5-HT from binding to SERT [6] which prevents absorption of 5-HT back into the presynapse terminal, where it is metabolized by monoamine oxidase or stored in secretory vesicles. [17] As a result, the 5-HT concentration increases at the somatodendritic area of the 5-HT neuron but not so much at the axon terminal area (demonstrated ...

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