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Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.
The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
Aromatase inhibitors (AIs) are a class of drugs used in the treatment of breast cancer in postmenopausal women and in men, [1] [2] and gynecomastia in men. They may also be used off-label to reduce estrogen conversion when supplementing testosterone exogenously. They may also be used for chemoprevention in women at high risk for breast cancer.
Estrogen deprivation therapy in the treatment of ER-positive breast cancer; Ovulation induction in infertility due to anovulation; Male hypogonadism; Gynecomastia (breast development in men) A component of hormone replacement therapy for transgender men
Ovarian cancer is staged using the FIGO staging system and uses information obtained after surgery, which can include a total abdominal hysterectomy via midline laparotomy, removal of (usually) both ovaries and fallopian tubes, (usually) the omentum, pelvic (peritoneal) washings, assessment of retroperitoneal lymph nodes (including the pelvic ...
Androgen replacement therapy formulations and dosages used in men Route Medication Major brand names Form Dosage Oral: Testosterone a – Tablet: 400–800 mg/day (in divided doses) Testosterone undecanoate: Andriol, Jatenzo: Capsule: 40–80 mg/2–4× day (with meals) Methyltestosterone b: Android, Metandren, Testred: Tablet: 10–50 mg/day ...
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