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Metastasis is a pathogenic agent's spreading from an initial or primary site to a different or secondary site within the host's body; [1] the term is typically used when referring to metastasis by a cancerous tumor. [2] The newly pathological sites, then, are metastases (mets).
It has the ability to spread beyond the place it started to invade multiple parts of the body. [4] Recent studies suggest that NORAD may be involved in the progression of certain cancer cells by increasing the amount of activity in genes that have the potential to cause uncontrollable cell growth ( oncogenes ), and decreasing the amount of ...
CNS metastasis is the spread and proliferation of cancer cells from their original tumour to form secondary tumours in portions of the central nervous system. [ 1 ] The process of tumour cells invading distant tissue is complex and obscure, but modern technology has permitted an enhanced detection of metastasis .
Stage migration is a change in the distribution of stages in a particular cancer population, induced by either a change in the staging system itself or else a change in technology which allows more sensitive detection of tumor spread and therefore more sensitivity in detecting spread of disease (e.g., the use of MRI scans).
The dispersed tumors are called metastatic tumors, while the original is called the primary tumor. Almost all cancers can metastasize. [38] Most cancer deaths are due to cancer that has metastasized. [39] Metastasis is common in the late stages of cancer and it can occur via the blood or the lymphatic system or both. The typical steps in ...
Cancer cells are cells that divide continually, forming solid tumors or flooding the blood or lymph with abnormal cells.Cell division is a normal process used by the body for growth and repair.
Research on CTC clusters and their role in metastasis continues to evolve, with the cancer exodus hypothesis offering a new perspective on how these clusters contribute to cancer progression. Detecting and analyzing CTC clusters provides critical prognostic information and could help guide therapeutic decisions for cancer patients.
Most solid cancers develop at their primary site but may then go on to metastasize or spread to other parts of the body. These further tumors are secondary tumors. Most cancers continue to be called after their primary site, as in breast cancer or lung cancer for example, even after they have spread to other parts of the body.