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Mastitis, a potentially fatal mammary gland infection, is the most common disease in dairy cattle in the United States and worldwide. It is also the most costly disease to the dairy industry . [ 1 ] Milk from cows suffering from mastitis has an increased somatic cell count .
Pirlimycin, sold under the brand name Pirsue, is used in the treatment of mastitis in cattle. [1] [3] [4] It is used as the salt pirlimycin hydrochloride and it belongs to the lincosamide class of antimicrobials. [1]
A CDC infographic on how antibiotic-resistant bacteria have the potential to spread from farm animals. The use of antibiotics in the husbandry of livestock includes treatment when ill (therapeutic), treatment of a group of animals when at least one is diagnosed with clinical infection (metaphylaxis [1]), and preventative treatment (prophylaxis).
When mastitis is associated with breastfeeding, the treatment has to balance short-term reduction of symptoms with solving the underlying problems that caused mastitis. For example, the Academy of Breastfeeding Medicine recommends against trying to "empty" the breasts, whether through pushing the baby to feed more or through using a breast pump ...
Corynebacterium bovis is a pathogenic bacterium that causes mastitis and pyelonephritis in cattle.. C. bovis is a facultatively anaerobic, Gram-positive organism, characterized by nonencapsulated, nonsporulated, immobile, straight or curved rods with a length of 1 to 8 μm and width of 0.3 to 0.8 μm, which forms ramified aggregations in culture (looking like "Chinese characters").
Examples of bacterial infections that could potentially be treated with tylosin include respiratory infections, metritis, and acute mastitis in cattle; mastitis in sheep and goats; enteritis, pneumonia, erysipelas, and infectious arthritis in swine; and soft-tissue infections in small animals.