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Docetaxel is in the taxane family of medications. [9] It works by disrupting the normal function of microtubules and thereby stopping cell division. [6] Docetaxel was patented in 1986 and approved for medical use in 1995. [10] It is on the World Health Organization's List of Essential Medicines. [11] Docetaxel is available as a generic ...
March 11, 2011, the US Food and Drug Administration (FDA) approved cancer drug docetaxel, a generic version by Hospira. Taxotere sales were approximately $1.2 billion in 2010. — Preceding unsigned comment added by Ocdncntx ( talk • contribs ) 21:42, 11 March 2011 (UTC) [ reply ]
Pfizer's lorlatinib was the first third-generation inhibitor and was approved in 2018 by the US FDA for ALK-positive NSCLC after progression on a first or second-generation inhibitor. Its macrocyclic structure was designed specifically to address some of the most recalcitrant resistance mutations.
"In 2012, the American Cancer Society estimates more than 28,000 men will die from the disease, making it the second leading cause of cancer death behind lung cancer. There are approximately ...
Paclitaxel is also known as Taxol and Onxol to be an anti-cancer drug. The drug is the first line treatment for ovarian, breast, lung, and colon cancer and the second line treatment for AIDS-related Kaposi's sarcoma. (Kaposi sarcoma is a cancer of the skin and mucous membranes that is commonly found in patients with acquired immunodeficiency ...
On Tuesday, the FDA approved NovoCure’s (NASDAQ:NVCR) Optune Lua for concurrent use with PD-1/PD-L1 inhibitors or docetaxel for adult patients with metastatic non-small cell lung cancer (mNSCLC ...
Paclitaxel (Taxol) and docetaxel (Taxotere) are widely used as chemotherapy agents. [ 2 ] [ 3 ] Cabazitaxel was FDA approved to treat hormone-refractory prostate cancer . Taxanes present difficulties in formulation as medicines because they are poorly soluble in water.
Pertuzumab is administered as an intravenous infusion in combination with trastuzumab and docetaxel as a first line treatment for HER2-positive metastatic breast cancer. [4] [3] It is also used in the same combination as a neoadjuvant (given to reduce the size of a tumor, prior to surgery or radiation) for HER2-positive early breast cancer; as of 2016 this use had not been shown to increase ...