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Other symptoms include thickening of the bone structure and accumulation of bone tissue, which both contribute to impaired joint mobility. Ligaments and cartilage can become ossified. [2] Most patients with skeletal fluorosis show side effects from the high fluoride dose such as ruptures of the stomach lining and nausea. [3]
Symptoms such as fractured hips in the elderly or brittle and weak bones may be caused by fluorine deficiency in the body. [14] Fluoride stimulates bone formation and increases bone density; [15] however, bone with excess fluoride content has an abnormal structure resulting in increased fragility. Thus, fluoride therapy results in large ...
Topical fluorides are fluoride-containing drugs indicated in prevention and treatment of dental caries, particularly in children's primary dentitions. [1] The dental-protecting property of topical fluoride can be attributed to multiple mechanisms of action, including the promotion of remineralization of decalcified enamel, the inhibition of the cariogenic microbial metabolism in dental plaque ...
Fluoride is a mainstay of dental care, whether it's delivered in a treatment at your dentist's office or in your toothpaste. But fluoride has become the focus of several conspiracy theories over ...
Fluoride exerts these effects by the demineralization and remineralization cycle. [23] The remineralization cycle, critical to decay prevention, occurs when fluoride is present in the oral cavity. After fluoride is swallowed it has a minimal effect. [10] [24] [25] Fluoride ions are involved in three principal reactions of remineralization: [24]
[15] [16] From roughly 7 years old thereafter, most children's permanent teeth would have undergone complete development (except their wisdom teeth), and therefore their susceptibility to fluorosis is greatly reduced, or even insignificant, despite the amount of intake of fluoride. [17] The severity of dental fluorosis depends on the amount of ...
The Dental Health Benefits of Flouride. Fluoride’s dental health benefits were discovered in the early 1900s when a dentist in Colorado noticed several patients had brown stains on their teeth ...
[2] [3] [4] Ingestion of fluoride can produce gastrointestinal discomfort at doses at least 15 to 20 times lower (0.2–0.3 mg/kg or 10 to 15 mg for a 50 kg person) than lethal doses. [5] Although it is helpful topically for dental health in low dosage, chronic ingestion of fluoride in large amounts interferes with bone formation.