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Acquired pure red cell aplasia. Myeloproliferative disorders. Polycythemia vera. Essential thrombocytosis. Myelofibrosis. Metabolic disorders. Amyloidoses. Amyloid light chain (AL) amyloidosis. Environmentally-induced diseases.
The patient is then treated with high-dose chemotherapy with or without radiotherapy with the intention of eradicating the patient's malignant cell population at the cost of partial or complete bone marrow ablation (destruction of patient's bone marrow's ability to grow new blood cells). The patient's own stored stem cells are then transfused ...
Hematopoietic stem cells (HSCs) are the stem cells [1] that give rise to other blood cells.This process is called haematopoiesis. [2] In vertebrates, the first definitive HSCs arise from the ventral endothelial wall of the embryonic aorta within the (midgestational) aorta-gonad-mesonephros region, through a process known as endothelial-to-hematopoietic transition.
Diseases and conditions where stem cell treatment is promising or emerging. Stem cells are being studied for several reasons. The molecules and exosomes released from stem cells are also being studied in an effort to make medications. [13]
A savior sibling may be the solution for any disease treated by hematopoietic stem cell transplantation.It is effective against genetically detectable (mostly monogenic) diseases, e.g. Fanconi anemia, [4] Diamond–Blackfan anemia [5] and β-thalassemia, in the ailing sibling, since the savior sibling can be selected to not have inherited the disease.
D016238. [edit on Wikidata] Apheresis (ἀφαίρεσις (aphairesis, "a taking away")) is a medical technology in which the blood of a person is passed through an apparatus that separates out one particular constituent and returns the remainder to the circulation. It is thus an extracorporeal therapy.
Regenerative medicine. A colony of human embryonic stem cells. Regenerative medicine deals with the "process of replacing, engineering or regenerating human or animal cells, tissues or organs to restore or establish normal function". [1] This field holds the promise of engineering damaged tissues and organs by stimulating the body's own repair ...
Multiple myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. [ 6 ] Often, no symptoms are noticed initially. [ 10 ] As it progresses, bone pain, anemia, renal insufficiency, and infections may occur. [ 10 ]
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