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The human virome is the total collection of viruses in and on the human body. [ 1 ][ 2 ][ 3 ] Viruses in the human body may infect both human cells and other microbes such as bacteria (as with bacteriophages). [ 4 ] Some viruses cause disease, while others may be asymptomatic. Certain viruses are also integrated into the human genome as ...
v. t. e. Virome refers to the assemblage of viruses [1][2] that is often investigated and described by metagenomic sequencing of viral nucleic acids [3] that are found associated with a particular ecosystem, organism or holobiont. The word is frequently used to describe environmental viral shotgun metagenomes. Viruses, including bacteriophages ...
A bacteriophage, or phage for short, is a virus that has the ability to infect bacteria and archaea, and can replicate inside of them. Phageome is a subcategory of virome, which is all of the viruses that are associated with a host or environment. [4] Phages make up the majority of most viromes and are currently understood as being the most ...
The double-stranded (ds)RNA viruses represent a diverse group of viruses that vary widely in host range (humans, animals, plants, fungi, [b] and bacteria), genome segment number (one to twelve), and virion organization (Triangulation number, capsid layers, spikes, turrets, etc.). Members of this group include the rotaviruses, which are the most ...
One such surveillance program is the Global Virome Project (GVP) an international collaborative research initiative based at the One Health Institute at the University of California, Davis. [ 29 ] [ 30 ] The GVP aims to boost infectious disease surveillance around the globe by using low cost sequencing methods in high risk countries to prevent ...
The viriome of a habitat or environment is the total virus content within it. [1] A viriome may relate to the viruses that inhabit a multicellular organism as well as the phages that are residing inside bacteria and archaea. This term exists in contrast to the virome, which more commonly refers to the collection of nucleic acids contained by ...
Double-stranded RNA viruses (dsRNA viruses) are a polyphyletic group of viruses that have double-stranded genomes made of ribonucleic acid.The double-stranded genome is used as a template by the viral RNA-dependent RNA polymerase (RdRp) to transcribe a positive-strand RNA functioning as messenger RNA (mRNA) for the host cell's ribosomes, which translate it into viral proteins.
A helper virus is a virus that allows an otherwise-deficient coinfecting virus to replicate. These can be naturally occurring as with Hepatitis D virus, which requires Hepatitis B virus to coinfect cells in order to replicate. Helper viruses are also commonly used to replicate and spread viral vectors for gene expression and gene therapy. [1]