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Tetrabenazine was approved in 2000 for treatment of chorea in Huntington's disease in the EU, and in 2008 in the US. [87] Although other drugs had been used "off label", tetrabenazine was the first approved treatment for Huntington's disease in the U.S. The compound has been known since the 1950s.
323.462 g·mol −1. Deutetrabenazine (trade name Austedo) is a vesicular monoamine transporter 2 inhibitor which is used for the treatment of chorea associated with Huntington's disease and tardive dyskinesia. Chemically, deutetrabenazine is an isotopic isomer of tetrabenazine in which six hydrogen atoms have been replaced by deuterium atoms.
Tetrabenazine is a drug for the symptomatic treatment of hyperkinetic movement disorders. It is sold under the brand names Nitoman and Xenazine among others. On August 15, 2008, the U.S. Food and Drug Administration approved the use of tetrabenazine to treat chorea associated with Huntington's disease. Although other drugs had been used " off ...
Tardive dyskinesia is believed to involve the neurotransmitter dopamine. Tardive dyskinesia (TD) is a disorder that results in involuntary repetitive body movements, which may include grimacing, sticking out the tongue or smacking the lips. [1] Additionally, there may be chorea or athetosis. [1] In about 20% of people with TD, the disorder ...
JERUSALEM (Reuters) -Teva Pharmaceutical Industries on Wednesday reported higher-than-expected second-quarter profit, boosted by a sharp gain in sales of its Austedo treatment for Huntington's ...
Treatment with the cancer drug restored function in the hippocampus in an Alzheimer's mouse model. ... KYN is known to play a role in brain aging and neurodegenerative disease. ... Huntington’s ...
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