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Food intake prior to testing may cause elevated levels, up to 20%. Normal level is defined as less than 150 mg/dL. [46] Borderline high is defined as 150 to 199 mg/dL. [46] High level is between 200 and 499 mg/dL. [46] Greater than 500 mg/dL is defined as very high, [46] and is associated with pancreatitis and requires medical treatment. [47]
If the lipase level is about 2.5 to 3 times that of amylase, it is an indication of pancreatitis due to alcohol. [14] Serum lipase is more sensitive and specific than serum amylase in the diagnosis of acute pancreatitis, and is the preferred test in the diagnosis. [15] [16]
Diagnosis requires 2 of the 3 following criteria: [citation needed] Characteristic acute onset of epigastric or vague abdominal pain that may radiate to the back (see signs and symptoms above) Serum amylase or lipase levels ≥ 3 times the upper limit of normal; An imaging study with characteristic changes.
Exocrine pancreatic insufficiency (EPI) is the inability to properly digest food due to a lack or reduction of digestive enzymes made by the pancreas.EPI can occur in humans and is prevalent in many conditions [1] such as cystic fibrosis, [2] Shwachman–Diamond syndrome, [3] different types of pancreatitis, [4] multiple types of diabetes mellitus (Type 1 and Type 2 diabetes), [5] advanced ...
The diagnosis of chronic pancreatitis is made based on the history and characteristics of symptoms combined with findings on radiologic imaging. [3] Serum amylase and lipase may be moderately elevated in cases of chronic pancreatitis.
GGT is also elevated in 30% of the hepatitis C patients. GGT can increase by 10 times in alcoholism. GGT can increase by 2 to 3 times in 50% of the patients with non-alcoholic liver disease. When GGT levels is elevated, the triglyceride level is elevated also. With insulin treatment, the GGT level can reduce.
Lipoprotein lipase deficiency is a genetic disorder in which a person has a defective gene for lipoprotein lipase, which leads to very high triglycerides, which in turn causes stomach pain and deposits of fat under the skin, and which can lead to problems with the pancreas and liver, which in turn can lead to diabetes.
Hepatic lipase (HL), also called hepatic triglyceride lipase (HTGL) or LIPC (for "lipase, hepatic"), is a form of lipase, catalyzing the hydrolysis of triacylglyceride. Hepatic lipase is coded by chromosome 15 and its gene is also often referred to as HTGL or LIPC . [ 5 ]