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In plants, selfing can occur as autogamous or geitonogamous pollinations and can have varying fitness affects that show up as autogamy depression. After several generations, inbreeding depression is likely to purge the deleterious alleles from the population because the individuals carrying them have mostly died or failed to reproduce.
Systematic inbreeding and maintenance of inbred strains of laboratory mice and rats is of great importance for biomedical research. The inbreeding guarantees a consistent and uniform animal model for experimental purposes and enables genetic studies in congenic and knock-out animals. In order to achieve a mouse strain that is considered inbred ...
Darwin's wife, Emma, was his first cousin, and he was concerned about the impact of inbreeding on his ten children, three of whom died at age ten or younger; three others had childless long-term marriages. [16] [17] [18] Humans do not seek to completely minimize inbreeding, but rather to maintain an optimal amount of inbreeding vs. outbreeding.
The term coefficient of relationship was defined by Sewall Wright in 1922, and was derived from his definition of the coefficient of inbreeding of 1921. The measure is most commonly used in genetics and genealogy. A coefficient of inbreeding can be calculated for an individual, and is typically one-half the coefficient of relationship between ...
Therefore the coefficient of inbreeding of individual G is = (+) = + = %. If the parents of an individual are not inbred themselves, the coefficient of inbreeding of the individual is one-half the coefficient of relationship between the parents. This can be verified in the previous example, as 12.5% is one-half of 25%, the coefficient of ...
Mixed mating systems are generally characterized by the frequency of selfing vs. outcrossing, but may include the production of asexual seeds through agamospermy. [2] The trade offs for each strategy depend on ecological conditions, pollinator abundance and herbivory [ 3 ] and parasite load. [ 4 ]
This should dramatically reduce the likelihood of inbreeding. Both protandry and protogyny are known to help prevent inbreeding in plants, [2] and many examples of sequential hermaphroditism attributable to inbreeding prevention have been identified in a wide variety of animals. [54]
Early-acting inbreeding depression is a form of selective embryo abortion that acts on embryos produced by selfing or mating of close relatives. [5] Inbreeding increases genetic homozygosity, allowing selection to elimination recessive, deleterious or lethal alleles (the presence of these deleterious alleles is referred to as genetic load). [7]