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Triamcinolone hexacetonide (brand name Aristospan; also known as triamcinolone acetonide 21-tebutate) is a synthetic glucocorticoid corticosteroid. [ 3 ] [ 4 ] [ 5 ] It is on the World Health Organization's List of Essential Medicines .
Triamcinolone is a synthetic pregnane corticosteroid and derivative of cortisol (hydrocortisone) and is also known as 1-dehydro-9α-fluoro-16α-hydroxyhydrocortisone or 9α-fluoro-16α-hydroxyprednisolone as well as 9α-fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione.
Triamcinolone acetonide, also known as 9α-fluoro-16α-hydroxyprednisolone 16α,17α-acetonide or as 9α-fluoro-11β,16α-17α,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone, is a synthetic halogenated cyclic ketal pregnane corticosteroid. [27] It is the C16α,17α acetonide of triamcinolone. [27]
Triamcinolone acetonide succinate (triamcinolone acetonide hemisuccinate) Triamcinolone benetonide (triamcinolone acetonide 21-(benzoyl-β-aminoisobutyrate)) Triamcinolone furetonide (triamcinolone acetonide 21-(2-benzofurancarboxylate)) Triamcinolone hexacetonide (triamcinolone acetonide 21-(tert-butylacetate))
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They are almost all C16α,17α cyclic ketals of corticosteroids. One of the most widely used corticosteroid cyclic ketals is triamcinolone acetonide, which is the C16α,17α acetonide (cyclic ketone with acetone) of triamcinolone. [1] This list mostly does not include esters of corticosteroid cyclic ketals, which are listed here instead.
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