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Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. [ 8 ] [ 9 ] It may also be used for hiccups and muscle spasms near the end of life, [ 9 ] and off-label to treat alcohol use disorder [ 10 ] [ 11 ] or opioid withdrawal symptoms. [ 12 ]
Upon analysis, scientists found that participants who stayed on standard statin treatment for their lifetime increased their quality-adjusted life years by 0.24-0.70, and those on higher-intensity ...
[1] [2] In 2018, there were over 45 million licensed drivers in the United States over the age of 65—a 60% increase from 2000. [3] Driving is said to help older adults stay mobile and independent, but as their age increases the risk of potentially injuring themselves or others significantly increases as well.
Suvorexant is used for the treatment of insomnia, characterized by difficulties with sleep onset and/or sleep maintenance, in adults. [2] [6] At a dose of 15 to 20 mg and in terms of treatment–placebo difference, it reduces time to sleep onset by up to 10 minutes, reduces time awake after sleep onset by about 15 to 30 minutes, and increases total sleep time by about 10 to 20 minutes. [2]
Major depression is more common in medically ill patients who are older than 70 years and hospitalized or institutionalized. Severe or chronic diseases associated with high rates of depression include stroke (30–60%), coronary heart disease (8–44%), cancer (1–40%), Parkinson's disease (40%), Alzheimer's disease (20–40%), and dementia ...
“Limbic” is related to the brain areas first involved, “age-related” and the name “LATE” itself refer to the onset of disease usually in persons aged 80 or older. “ TDP-43 ” indicates the aberrant mis-folded protein (or proteinopathy ) deposits in the brain that characterize LATE, and “ encephalopathy ” means illness of brain.
Diclofenac, sold under the brand name Voltaren among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases such as gout. [6] [9] It can be taken orally (swallowed by mouth), inserted rectally as a suppository, injected intramuscularly, injected intravenously, applied to the skin topically, or through eye drops.
The risk of postoperative urinary retention increases up to 2.11 fold for people older than 60 years. [ 6 ] Medications: Anticholinergics and medications with anticholinergic properties, alpha-adrenergic agonists , opiates , nonsteroidal anti-inflammatories (NSAIDs), calcium-channel blockers and beta-adrenergic agonists , may increase the risk.