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Pharmacology is the science of drugs and medications, [1] including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. [ 2 ]
In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect. [2] A mechanism of action usually includes mention of the specific molecular targets to which the drug binds, such as an enzyme or receptor . [ 3 ]
As a result of their efforts, the American College of Clinical Pharmacology (ACCP) was founded on September 11, 1969. [ 2 ] The mission is to improve health by optimizing therapeutics and to provide leadership and education that enables the generation, integration and translation of scientific knowledge to optimize research, development and ...
With worldwide research into pharmacology as well as medicine, traditional medicines or ancient herbal medicines are often translated into modern remedies, such as the anti-malarial group of drugs called artemisinin isolated from Artemisia annua herb, a herb that was known in Chinese medicine to treat fever.
Lecanemab may cause amyloid-related imaging abnormalities (ARIA). ARIA is often asymptomatic, but serious and life-threatening events rarely may occur.ARIA most commonly presents as temporary swelling of the brain that usually resolves over time and may be accompanied by small spots of bleeding in or on the surface of the brain, though some people may have symptoms such as headache, confusion ...
Molecular Pharmacology is a peer-reviewed scientific journal published by the American Society for Pharmacology and Experimental Therapeutics since 1965. It is indexed in MEDLINE, Meta, Scopus, and other databases. [1] [2] According to the Journal Citation Reports, the journal received a 2017 impact factor of 3.987. [3]
A key assumption underlying the CPIC guidelines is that clinical high-throughput and pre-emptive (pre-prescription) genotyping will become more widespread, and that clinicians will be faced with having patients’ genotypes available even if they have not explicitly ordered a test with a specific drug in mind.
GAD is a common disorder in which the central feature is excessively worrying about numerous events. Key symptoms include excessive anxiety about events and issues going on around them and difficulty controlling worrisome thoughts that persists for at least 6 months. Antidepressants provide a modest to moderate reduction in anxiety in GAD. [46]