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It is not certain what causes this pain, but researchers have proposed that the small numerous stones seen in MSK may cause obstruction of the small tubules and collecting ducts in the kidney. This pain can be constant, can often be debilitating and treatment is challenging. Narcotic medication, even in large quantities, is sometimes not adequate.
The different colors indicate embryologic origin of structure: a) red = metanephric duct , b) yellow = urogenital sinus (bladder and urethra), c) blue = Wolffian duct (Gartner's ducts in female, seminal vesicles and vasa deferentia in male), pink = Müllerian ducts (vagina in female, prostatic utricle in male), green = hindgut . Specialty
During the fifth week of gestation, the mesonephric duct develops an outpouching, the ureteric bud, near its attachment to the cloaca. This bud, also called the metanephrogenic diverticulum, grows posteriorly and towards the head of the embryo. The elongated stalk of the ureteric bud, called the metanephric duct, later forms the ureter.
The metanephrogenic blastema or metanephric blastema (or metanephric mesenchyme, or metanephric mesoderm) is one of the two embryological structures that give rise to the kidney, the other being the ureteric bud. The metanephric blastema mostly develops into nephrons, but can also form parts of the collecting duct system.
The signs and symptoms of hydronephrosis depend upon whether the obstruction is acute or chronic, partial or complete, unilateral or bilateral.Hydronephrosis that occurs acutely with sudden onset (as caused by a kidney stone) can cause intense pain in the flank area (between the hips and ribs) known as a renal colic.
The ureteric bud, also known as the metanephric diverticulum, [1]: 50 is a protrusion from the mesonephric duct during the development of the urinary and reproductive organs. [ 2 ] [ 3 ] It later develops into a conduit for urine drainage from the kidneys, which, in contrast, originate from the metanephric blastema .
There is a small association between Gartner's duct cysts and metanephric urinary anomalies, such as ectopic ureter and ipsilateral renal hypoplasia. [5] Symptoms of a Gartner's duct cyst include: infections, bladder dysfunction, abdominal pain, vaginal discharge, and urinary incontinence. [6] The size of the cyst is usually less than 2 cm.
Kidney stones – deviant orientation of kidneys combined with slow urine flow and kidney obstruction may increase the risk of developing kidney stones. Treatment is further complicated if patient possesses aberrant skeletal anatomy. [5] It is estimated 36% of patients with horseshoe kidneys will develop kidney stones. [6]