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The number of neurons in the spiral ganglion is estimated to be about 35,000–50,000. [1] Two apparent subtypes of spiral ganglion cells exist. Type I spiral ganglion cells comprise the vast majority of spiral ganglion cells (90–95% in cats and 88% in humans [2]), and exclusively innervate the inner hair cells. They are myelinated, bipolar ...
Retinal ganglion cell (RGC) found in the ganglion cell layer of the retina [1] Cells that reside in the adrenal medulla, where they are involved in the sympathetic nervous system's release of epinephrine and norepinephrine into the blood stream; Cells of the sympathetic ganglia; Cells of the parasympathetic ganglia; Cells of the spiral ganglia [2]
The superior and inferior divisions of the vestibular nerve meet at the ganglion.Thereon, the fibers of second-order neurons of the vestibular nerve merge with those of the cochlear nerve (whose first-order neurons have already synapsed at the spiral ganglion) to proceed towards the CNS as a single unified vestibulocochlear nerve (cranial nerve VIII).
A ganglion (pl.: ganglia) is a group of neuron cell bodies in the peripheral nervous system. In the somatic nervous system , this includes dorsal root ganglia and trigeminal ganglia among a few others.
The cell bodies of the cochlear nerve lie within the cochlea and collectively form the spiral ganglion, named for the spiral shape it shares with the cochlea. These central axons exit the cochlea at its base and form a nerve trunk , which, in humans, is approximately one inch long.
The hair cells function as a transducer, converting the mechanical movement of the basilar membrane into electrical voltage, in a process requiring ATP from the stria vascularis as an energy source. The depolarized hair cell releases neurotransmitters across a synapse to primary auditory neurons of the spiral ganglion.
The vestibular nerve is one of the two branches of the vestibulocochlear nerve (the cochlear nerve being the other). In humans the vestibular nerve transmits sensory information from vestibular hair cells located in the two otolith organs (the utricle and the saccule) and the three semicircular canals via the vestibular ganglion of Scarpa.
The LOCS (originating from both the intrinsic and shell neurons) contains unmyelinated fibres that synapse with the dendrites of the Type I spiral ganglion cells projecting to the inner hair cells. While the intrinsic LOCS neurons tend to be small (~10 to 15 μm in diameter), and the shell OC neurons are larger (~25 μm in diameter), it is the ...