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Hyperchloremia is an electrolyte disturbance in which there is an elevated level of chloride ions in the blood. [1] The normal serum range for chloride is 96 to 106 mEq/L, [2] therefore chloride levels at or above 110 mEq/L usually indicate kidney dysfunction as it is a regulator of chloride concentration. [3]
The levels of chloride in the blood can help determine if there are underlying metabolic disorders. [20] Generally, chloride has an inverse relationship with bicarbonate, an electrolyte that indicates acid-base status. [20] Overall, treatment of chloride imbalances involve addressing the underlying cause rather than supplementing or avoiding ...
Loop diuretics are 90% bonded to proteins and are secreted into the proximal convoluted tubule through organic anion transporter 1 (OAT-1), OAT-2, and ABCC4.Loop diuretics act on the Na +-K +-2Cl − symporter (NKCC2) in the thick ascending limb of the loop of Henle to inhibit sodium, chloride and potassium reabsorption.
Type 1 diabetes, also known as "Juvenile-onset" Diabetes is increasing in children and adolescents under the age of 15. [128] Type 1 diabetes is an autoimmune disease where the body attacks the beta-cells produced by the pancreas; therefore, causing the body to have insulin deficiency. [129]
Dr. Thomas O’Brien and his wife Ruth Reardon O’Brien, the parents of late night comedian Conan O’Brien, have died three days apart. Thomas was 95 and Ruth was 92. Thomas died on Monday, Dec ...
TDM interpretation: an anticancer drug is given to a patient at a dosage of 400 mg every day at 8:00 am. A TDM sample is obtained at 6:00 am, showing a drug concentration of 0.46 mg/L. 1) Regarding “normality”, the result is around the 25th percentile, suggesting a rather high drug clearance in this patient.
The Broncos (12-1) take on the Nittany Lions (11-2) at 7:30 p.m. ET on Tuesday in the Fiesta Bowl from State Farm Stadium in Glendale, Arizona, with a chance to advance to the semifinals.
The Cooper Flagg era in Durham is off and running. Flagg and No. 7 Duke cruised to a dominant 96-62 win over Maine on Monday night to officially tip off the 2024-25 men's college basketball season ...
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