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Benznidazole is an antiparasitic medication used in the treatment of Chagas disease. [2] While it is highly effective in early disease, the effectiveness decreases in those who have long-term infection. [3] It is the first-line treatment given its moderate side effects compared to nifurtimox. [1] It is taken by mouth. [2] Side effects are ...
Nifurtimox, sold under the brand name Lampit, is a medication used to treat Chagas disease and sleeping sickness. [2] [4] For sleeping sickness it is used together with eflornithine in nifurtimox-eflornithine combination treatment. [4] In Chagas disease it is a second-line option to benznidazole. [5] It is given by mouth. [2]
Chagas disease is managed using antiparasitic drugs to eliminate T. cruzi from the body, and symptomatic treatment to address the effects of the infection. [6] As of 2018, benznidazole and nifurtimox were the antiparasitic drugs of choice for treating Chagas disease, [2] though benznidazole is the only drug available in most of Latin America. [40]
Doctors, researchers, and patient advocates say the U.S. could be doing far more to combat Chagas, which causes serious heart disease in an estimated 30% of infected people and can also lead to ...
Megazol (CL 64855) is a nitroimidazole based drug that cures some protozoan infections.. A study of nitroimidazoles found the drug extremely effective against T. cruzi and T. brucei which cause Chagas disease and African sleeping sickness, respectively.
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Latina author Daisy Hernández discussed her book "The Kissing Bug" and why Chagas' disease, which mostly impacts Hispanics, has been largely ignored in the U.S. This deadly 'kissing bug' has been ...
The logo of the Drugs for Neglected Diseases initiative (DNDi) The Drugs for Neglected Diseases initiative (DNDi) is a collaborative, patients' needs-driven, non-profit drug research and development (R&D) organization that is developing new treatments for neglected diseases, notably leishmaniasis, sleeping sickness (human African trypanosomiasis, HAT), Chagas disease, [1] malaria, filarial ...