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The most common side effects are musculoskeletal pain, peripheral edema (swelling of legs and hands), atrial fibrillation, and arthralgia (joint pain). [6] Other common side effects include bleeding, constipation, gout, and rash. [4] It is made from the omega−3 fatty acid eicosapentaenoic acid (EPA). [6]
[4] [6] [7] Omega-3-acid ethyl esters are taken by mouth. [4] Common side effects include burping, nausea, and an upset abdomen. [4] [6] Serious side effects may include liver problems and anaphylaxis. [4] While use in pregnancy has not been well studied, some omega−3 fatty acids appear beneficial. [1] How it works is not entirely clear. [4]
A 2019 review found that omega−3 supplements have no effect on prevention and treatment of type 2 diabetes. [167] [168] A 2021 meta-analysis found that supplementation with omega−3 had positive effects on diabetes biomarkers, such as fasting blood glucose and insulin resistance. [169]
New research links omega-6 fatty acids, commonly found in seed oils, and colon cancer growth. But there’s more to the story—and study if you read it carefully.
Omega−3-carboxylic acids are used in addition to changes in diet to reduce triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia. [6]Intake of large doses (2.0 to 4.0 g/day) of long-chain omega−3 fatty acids as prescription drugs or dietary supplements are generally required to achieve significant (> 15%) lowering of triglycerides, and at those doses the effects ...
Intake of large doses (2.0 to 4.0 g/day) of long-chain omega−3 fatty acids as prescription drugs or dietary supplements are generally required to achieve significant (> 15%) lowering of triglycerides, and at those doses the effects can be significant (from 20% to 35% and even up to 45% in individuals with levels greater than 500 mg/dL).