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Vancomycin is a glycopeptide antibiotic medication used to treat certain bacterial infections. [7] It is administered intravenously (injection into a vein) to treat complicated skin infections, bloodstream infections, endocarditis, bone and joint infections, and meningitis caused by methicillin-resistant Staphylococcus aureus. [8]
The condition is commonly associated with vascular and cardiac changes associated with aging but can be caused by many other conditions, including congestive heart failure, kidney failure, liver cirrhosis, portal hypertension, trauma, alcoholism, altitude sickness, pregnancy, hypertension, sickle cell anemia, a compromised lymphatic system or merely long periods of time sitting or standing ...
Swelling: Some individuals may experience slight swelling (edema) in the lower legs alongside the rash. This swelling is typically mild and localized to the affected areas. [3] [2] Burning sensation: A burning or stinging sensation in the affected skin is commonly reported. This discomfort can range from mild to moderate in intensity. [3] [6]
Both strengths can work well for everyday use, athletic recovery, travel, and mild swelling and aches. However, anything above 20 mmHg is prescribed by doctors for specific conditions.
Glycopeptide antibiotics are a class of drugs of microbial origin that are composed of glycosylated cyclic or polycyclic nonribosomal peptides.Significant glycopeptide antibiotics include the anti-infective antibiotics vancomycin, teicoplanin, telavancin, ramoplanin, avoparcin and decaplanin, corbomycin, complestatin and the antitumor antibiotic bleomycin.
The legs and face are the most common sites involved, although cellulitis can occur on any part of the body. [1] The leg is typically affected following a break in the skin. [1] Other risk factors include obesity, leg swelling, and old age. [1] For facial infections, a break in the skin beforehand is not usually the case. [1]
In men, lower-limb primary lymphedema is most common, occurring in one or both legs. Some cases of lymphedema may be associated with other vascular abnormalities. [4] [citation needed] Secondary lymphedema affects both men and women, and, in Western countries, is most commonly due to cancer treatment. [14]
[19] [20] Both ovarian and internal iliac vein reflux causes leg varicose veins. This condition affects 14% of women with varicose veins or 20% of women who have had vaginal delivery and have leg varicose veins. [21] In addition, evidence suggests that failing to look for and treat pelvic vein reflux can be a cause of recurrent varicose veins. [22]