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In centrifugation the clearing factor or k factor represents the relative pelleting efficiency of a given centrifuge rotor at maximum rotation speed. It can be used to estimate the time t {\displaystyle t} (in hours) required for sedimentation of a fraction with a known sedimentation coefficient s {\displaystyle s} (in svedbergs ):
A standard ultracentrifuge by manufacturer Beckman Coulter. An ultracentrifuge is a centrifuge optimized for spinning a rotor at very high speeds, capable of generating acceleration as high as 1 000 000 g (approx. 9 800 km/s²). [1] There are two kinds of ultracentrifuges, the preparative and the analytical ultracentrifuge.
Beckman Coulter, Inc. is a Danaher Corporation company that develops, manufactures, and markets products relevant to biomedical testing. It operates in the industries of diagnostics and life sciences .
Beckman Coulter (now Danaher) has previously manufactured chain termination and capillary electrophoresis-based DNA sequencers under the model name CEQ, including the CEQ 8000. [27] The company now produces the GeXP Genetic Analysis System, which uses dye terminator sequencing . [ 28 ]
Benchtop fixed-angle centrifuge, or swinging bucket centrifuge Intact (eukaryotic) cells, macroscopic debris Varies depending on sample Gently lysed cells (e.g. dounce homogenizer) 600 x g 10 min Benchtop fixed-angle centrifuge, or swinging bucket centrifuge Nuclei Cytosol, non-nuclei organelles Supernatant of previous row 15,000 x g 20 min
A tricanter centrifuge operates on a similar principle to decanter centrifuges but instead separates three phases, consisting of a suspended solids phase and two immiscible liquids. [5] Sedimentation of the suspended solids occurs as normal where they accumulate on the wall of the bowl and are conveyed out of the centrifuge.
Arnold Orville Beckman (April 10, 1900 – May 18, 2004) was an American chemist, inventor, investor, and philanthropist. While a professor at California Institute of Technology, he founded Beckman Instruments based on his 1934 invention of the pH meter, a device for measuring acidity (and alkalinity), later considered to have "revolutionized the study of chemistry and biology". [1]
Arnold Orville Beckman, chemist and entrepreneur; Beckman Coulter, a biomedical laboratory instruments company founded by Arnold O. Beckman; 3737 Beckman, an asteroid; Institutes and research centers supported by the Arnold and Mabel Beckman Foundation Beckman Center for Molecular and Genetic Medicine at Stanford University, Stanford, California