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Lithium orotate (C 5 H 3 LiN 2 O 4) is a salt of orotic acid and lithium.It is available as the monohydrate, LiC 5 H 3 N 2 O 4 ·H 2 O. [1] In this compound, lithium is non-covalently bound to an orotate ion, rather than to a carbonate or other ion, and like other salts, dissolves in solution to produce free lithium ions.
Orotic acid is a Bronsted acid and its conjugate base, the orotate anion, is able to bind to metals. Lithium orotate, for example, has been investigated for use in treating alcoholism, [4] [5] and complexes of cobalt, manganese, nickel, and zinc are known. [6]
7), lithium sulfate, lithium chloride, and lithium orotate. [ 139 ] [ 140 ] Nanoparticles and microemulsions have also been invented as drug delivery mechanisms. As of 2020, there is a lack of evidence that alternate formulations or salts of lithium would reduce the need for monitoring serum lithium levels or lower systemic toxicity.
The starting dose is usually 75 milligrams, but it can be increased to a maximum safe dose of 225 milligrams daily. Similar to SNRIs, venlafaxine can come with a mixed bag of side effects ...
Mar. 24—(StatePoint) About 7,000 children in the United States visit emergency rooms for battery-related injuries each year, according to the National Electronic Injury Surveillance System.
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