Ads
related to: beta thalassemia medications to avoid list of side effects fluorouracil- Learn About Treatment
Learn About the Treatment Journey.
Watch the Video to Learn More.
- Patient FAQs
Get Answers to Common Questions.
Understand the Potential Risks.
- Safety and Side Effects
Review the Important Safety
Information & Side Effects.
- Find an ATC
Find an Authorized Treatment Center
On the Official Patient Website.
- Patient Information
View Important Patient Information.
Understand the Treatment.
- View Discussion Guides
Download Treatment Brochures,
Discussion Guides, and More.
- Learn About Treatment
Search results
Results From The WOW.Com Content Network
Most of the iron-drug complex is therefore excreted within three to four hours following administration, the excretion occurring mostly in urine (90%). [16] When comparing deferiprone to deferoxamine, they both bind iron with similar efficiency. However, drugs with different properties are able to access different iron pools.
Luspatercept, sold under the brand name Reblozyl, is a medication used for the treatment of anemia in beta thalassemia and myelodysplastic syndromes. [5] The US Food and Drug Administration (FDA) considers it to be a first-in-class medication. [8]
Deferiprone, sold under the brand name Ferriprox among others, is a medication that chelates iron and is used to treat iron overload in thalassaemia major. [5] It was first approved and indicated for use in treating thalassaemia major in 1994 [6] and had been licensed for use in the European Union for many years while awaiting approval in Canada and in the United States. [5]
Its main use is to reduce chronic iron overload in patients who are receiving long-term blood transfusions for conditions such as beta-thalassemia and other chronic anemias. [4] [5] It is the first oral medication approved in the United States for this purpose. [6] It was approved by the US Food and Drug Administration (FDA) in November 2005.
Beta thalassemia minor can also present as beta thalassemia silent carriers; those who inherit a beta thalassemic mutation but have no hematologic abnormalities nor symptoms. [8] Some people with thalassemia are susceptible to health complications that involve the spleen (hypersplenism) and gallstones (due to hyperbilirubinemia from peripheral ...
There are two approved forms of gene therapy for beta thalassemia. [96] [97] Betibeglogene autotemcel, sold under the brand name Zynteglo, is a gene therapy for the treatment for beta thalassemia which adds a healthy beta-globin gene to the HSCs. [98] It was approved for medical use in the United States in August 2022.
Fluorouracil (5-FU, 5-fluorouracil), sold under the brand name Adrucil among others, is a cytotoxic chemotherapy medication used to treat cancer. [3] By intravenous injection it is used for treatment of colorectal cancer , oesophageal cancer , stomach cancer , pancreatic cancer , breast cancer , and cervical cancer . [ 3 ]
Betibeglogene autotemcel, sold under the brand name Zynteglo, is a gene therapy for the treatment for beta thalassemia. [1] [5] [2] It was developed by Bluebird Bio and was given breakthrough therapy designation by the US Food and Drug Administration in February 2015.
Ads
related to: beta thalassemia medications to avoid list of side effects fluorouracil