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2. Your Gout Guide: From Symptoms to Treatment - AOL

   www.aol.com/gout-guide-symptoms-treatment...

   Uric acid is a normal waste product made by the body, but in some people, it can accumulate at higher levels and lead to gout. Gout can be divided into four stages: Hyperuricemia.

3. Hyperuricemia - Wikipedia

   en.wikipedia.org/wiki/Hyperuricemia

   Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [5] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...

4. Uric acid - Wikipedia

   en.wikipedia.org/wiki/Uric_acid

   Uric acid displays lactam–lactim tautomerism. [4] Uric acid crystallizes in the lactam form, [5] with computational chemistry also indicating that tautomer to be the most stable. [6] Uric acid is a diprotic acid with pK a1 = 5.4 and pK a2 = 10.3. [7] At physiological pH, urate predominates in solution. [medical citation needed]

5. Uricosuric - Wikipedia

   en.wikipedia.org/wiki/Uricosuric

   By decreasing plasma uric acid levels, help dissolve these crystals, while limiting the formation of new ones. However, the increased uric acid levels in urine can contribute to kidney stones. Thus, use of these drugs is contraindicated in persons already with a high urine concentration of uric acid (hyperuricosuria). In borderline cases ...

6. Dr. David Perlmutter’s ‘Drop Acid’ Book Shares Truth About ...

   www.aol.com/entertainment/dr-david-perlmutter...

   Throughout Drop Acid, Dr. Perlmutter offers suggestions and tips on maintaining lower uric values as well as a road map to addressing these hidden dangers. Per the description it also features ...

7. Pegloticase - Wikipedia

   en.wikipedia.org/wiki/Pegloticase

   Pegloticase is given as an intravenous infusion every two weeks, [6] and has been found to reduce uric acid levels in this population. [7] There is moderate quality evidence that It is useful for tophi but has a high rate of side effects and withdrawals due to adverse events. [8] About 40% of people develop resistance to the medication over ...