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A monohybrid cross is a cross between two organisms with different variations at one genetic locus of interest. [ 1 ] [ 2 ] The character(s) being studied in a monohybrid cross are governed by two or multiple variations for a single location of a gene.
The first uses of test crosses were in Gregor Mendel’s experiments in plant hybridization.While studying the inheritance of dominant and recessive traits in pea plants, he explains that the “signification” (now termed zygosity) of an individual for a dominant trait is determined by the expression patterns of the following generation.
In this monohybrid cross the dominant allele encodes for the colour red and the recessive allele encodes for the colour white. Mendel's work was published in 1866 as "Versuche über Pflanzen-Hybriden" ( Experiments on Plant Hybridisation ) in the Verhandlungen des Naturforschenden Vereins zu Brünn (Proceedings of the Natural History Society of ...
Punnett squares for each combination of parents' colour vision status giving probabilities of their offsprings' status, each cell having 25% probability in theory. The Punnett square is a square diagram that is used to predict the genotypes of a particular cross or breeding experiment.
In organic chemistry, a cross-coupling reaction is a reaction where two different fragments are joined. Cross-couplings are a subset of the more general coupling reactions. Often cross-coupling reactions require metal catalysts. One important reaction type is this:
For instance, an inter-strand cross-link (caused by exposure to a cross-linking agent such as mitomycin C) can be repaired by HRR. Two types of recombinant product are produced. Indicated on the right side is a "crossover" (CO) type, where the flanking regions of the chromosomes are exchanged, and on the left side, a "non-crossover" (NCO) type ...
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The first theory rests upon the idea that meiosis evolved as another method of DNA repair, and thus crossing-over is a novel way to replace possibly damaged sections of DNA. [9] The second theory comes from the idea that meiosis evolved from bacterial transformation , with the function of propagating diversity.