Ad
related to: tata box transcription protein
Search results
Results From The WOW.Com Content Network
The TATA box was first identified in 1978 [1] as a component of eukaryotic promoters. Transcription is initiated at the TATA box in TATA-containing genes. The TATA box is the binding site of the TATA-binding protein (TBP) and other transcription factors in some eukaryotic genes.
The TATA-binding protein (TBP) is a general transcription factor that binds to a DNA sequence called the TATA box. This DNA sequence is found about 30 base pairs upstream of the transcription start site in some eukaryotic gene promoters .
TATA-box binding protein like 2 is a protein that in humans is encoded by the TBPL2 gene. [5] The TBPL2 protein is also known as TBP-related factor 3 (TRF3) and TATA binding protein 2 (TBP2). The protein was independently discovered in three laboratories as a vertebrate-specific family member of TATA-binding protein (TBP).
237336 Ensembl ENSG00000028839 ENSMUSG00000071359 UniProt P62380 Q7Z6T9 P62340 RefSeq (mRNA) NM_004865 NM_001253676 NM_011603 RefSeq (protein) NP_001240605 NP_004856 NP_035733 Location (UCSC) Chr 6: 133.95 – 133.99 Mb Chr 10: 22.58 – 22.61 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse TATA box-binding protein-like protein 1 is a protein that in humans is encoded by the TBPL1 ...
TFIID is composed of the TATA-binding protein and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation.
The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors.
The GC elements are bound by transcription factors and have similar functions to enhancers. [2] Some known GC box-binding proteins include Sp1, Krox/Egr, Wilms' tumor, MIGI, and CREA. [1] The GC box is commonly the binding site for zinc finger proteins. An alpha helix section of the protein corresponds with a major groove in the DNA.
TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation.