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Although exome sequencing is more expensive than hybridization-based technologies on a per-sample basis, its cost has been decreasing due to the falling cost and increased throughput of whole genome sequencing. [citation needed]
As the costs of sequencing continued to plummet, in 2008, Illumina announced that it had sequenced an individual genome for $100,000 in reagent costs. Applied Biosystems countered by saying the cost on its platform was $60,000. [17] Pacific Biosciences became the latest entrant in what The New York Times called "a heated race for the '$1,000 ...
The cost must also take into account personnel costs, data processing costs, legal, communications and other costs. One way to assess this is via commercial offerings. The first such whole diploid genome sequencing (6 billion bp, 3 billion from each parent) was from Knome and their price dropped from $350,000 in 2008 to $99,000 in 2009.
The Carlson curve is a term to describe the rate of DNA sequencing or cost per sequenced base as a function of time. [1] It is the biotechnological equivalent of Moore's law. Carlson predicted that the doubling time of DNA sequencing technologies (measured by cost and performance) would be at least as fast as Moore's law. [2]
To reduce the costs from sequencing whole genomes, many methods that enrich specific genomic regions of interest have been proposed. ... Low amount of sample DNA ...
The company is also working on process improvements to bring down the internal cost to around $100 per genome, excluding sample-prep and labor costs. [16] [17] According to the National Human Genome Research Institute (NHGRI), the costs to sequence the entire genome has significantly decreased from over $95 million in 2001 to $7,666 in January ...
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