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A bioassay is a biochemical test to estimate the potency of a sample compound. Usually this potency can only be measured relative to a standard compound. [3] [1] A typical bioassay involves a stimulus (ex. drugs) applied to a subject (ex. animals, tissues, plants). The corresponding response (ex. death) of the subject is thereby triggered and ...
Tests of necessity, among which are methods of lesioning or gene knockout, and tests of sufficiency, among which are methods of isolation or discrete stimulation of factors, have become important in current-day experimental designs, and application of these tests have led to a number of notable discoveries and findings in the biological sciences.
Industrial Bio-Test Laboratories (IBT Labs) was an American industrial product safety testing laboratory. [1] [2] [3] IBT conducted significant quantities of research for pharmaceutical companies, chemical manufacturers and other industrial clients; at its height during the 1950s, 1960s, and 1970s, IBT operated the largest facility of its kind and performed more than one-third of all ...
Experimental biology is the set of approaches in the field of biology concerned with the conduction of experiments to investigate and understand biological phenomena. The term is opposed to theoretical biology which is concerned with the mathematical modelling and abstractions of the biological systems.
Biological specimens in an elementary school science lab. A biological specimen (also called a biospecimen) is a biological laboratory specimen held by a biorepository for research. Such a specimen would be taken by sampling so as to be representative of any other specimen taken from the source of the specimen. When biological specimens are ...
In 2020, it was announced that Google's AlphaFold, a neural network based on DeepMind artificial intelligence, is capable of predicting a protein's final shape based solely on its amino-acid chain with an accuracy of around 90% on a test sample of proteins used by the team.
An antibody that recognizes the protein can be added to this mixture to create an even larger complex with a greater shift. This method is referred to as a supershift assay, and is used to unambiguously identify a protein present in the protein – nucleic acid complex.
Bioanalysis also applies to drugs used for illicit purposes, forensic investigations, anti-doping testing in sports, and environmental concerns. Bioanalysis was traditionally thought of in terms of measuring small molecule drugs.