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A polyphenol antioxidant is a hypothesized type of antioxidant studied in vitro. Numbering over 4,000 distinct chemical structures mostly from plants , such polyphenols have not been demonstrated to be antioxidants in vivo .
Polyphenols were once considered as antioxidants, but this concept is obsolete. [67] Most polyphenols are metabolized by catechol-O-methyltransferase, and therefore do not have the chemical structure allowing antioxidant activity in vivo; they may exert biological activity as signaling molecules.
On the contrary, research indicates that although polyphenols are antioxidants in vitro, antioxidant effects in vivo are probably negligible or absent. [3] [4] [5] By non-antioxidant mechanisms still undefined, polyphenols may affect mechanisms of cardiovascular disease or cancer. [6]
As a source of monounsaturated fats and antioxidants like vitamin E and polyphenols, olive oil may help reduce inflammation and oxidative stress, which are linked to neurodegenerative diseases ...
Antioxidants protect the body from the harmful effects of free radicals by bolstering cellular function and reducing oxidative stress. ... Resveratrol is a natural polyphenol that has been touted ...
As part of their adaptation from marine life, terrestrial plants began producing non-marine antioxidants such as ascorbic acid (), polyphenols, and tocopherols.The evolution of angiosperm plants between 50 and 200 million years ago resulted in the development of many antioxidant pigments – particularly during the Jurassic period – as chemical defences against reactive oxygen species that ...
Olive oil is packed with antioxidants like polyphenols that help reduce inflammation, another essential factor for good heart health. ... Tomatoes contain an antioxidant called lycopene that can ...
Resveratrol (3,5,4′-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural phenol or polyphenol and a phytoalexin produced by several plants in response to injury or when the plant is under attack by pathogens, such as bacteria or fungi.