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In vitro at high experimental doses, polyphenols may affect cell-to-cell signaling, receptor sensitivity, inflammatory enzyme activity or gene regulation. [3] [4] None of these hypothetical effects has been confirmed in humans by high-quality clinical research, as of 2020. [1]
Polyphenols are a large, diverse group of compounds, making it difficult to determine their biological effects. [56] They are not considered nutrients, as they are not used for growth, survival or reproduction, nor do they provide dietary energy. Therefore, they do not have recommended daily intake levels, as exist for vitamins, minerals, and ...
Polyphenols in plant-based foods may trigger gastrointestinal hormones that could help reduce a person's risk for both obesity and type 2 diabetes, new research indicates.
Previous research has also noted that the antioxidants and polyphenols in chia seeds are the same components that can be helpful against breast, colorectal, liver and pancreatic cancers. Chia ...
To begin with, green tea contains polyphenols, which are considered a type of antioxidant, says Coleen Wysocki, M.S., RDN, owner of Zest Nutrition. Although there are thousands of polyphenols ...
Adverse effects resulted mainly from long-term use (weeks or longer) and daily doses of 1000 mg or higher, causing nausea, stomach pain, flatulence, and diarrhea. [6] A review of 136 patients in seven studies who were given more than 500 mg for a month showed 25 cases of diarrhea, 8 cases of abdominal pain, 7 cases of nausea, and 5 cases of ...
Health benefits: Few studies have examined the effects of ginger tea specifically, but various ginger preparations have been shown to help alleviate pregnancy-related nausea.
In animals and humans, after ingestion, natural phenols become part of the xenobiotic metabolism. In subsequent phase II reactions, these activated metabolites are conjugated with charged species such as glutathione, sulfate, glycine or glucuronic acid. These reactions are catalysed by a large group of broad-specificity transferases.