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Guaifenesin might act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi via stimulation of the gastric mucosa. . This stimulation leads to an increased parasympathetic activity in the respiratory tract via the so-called gastro-pulmonary reflex, although some in vitro studies suggested that it might also act directly on the ...
Rhinitis medicamentosa (or RM, also known as rebound congestion) is a condition of rebound nasal congestion suspected to be brought on by extended use of topical decongestants (e.g., oxymetazoline, phenylephrine, xylometazoline, and naphazoline nasal sprays) and certain oral medications (e.g., sympathomimetic amines and various 2-imidazolines) that constrict blood vessels in the lining of the ...
In over-the-counter formulations, DXM is often combined with acetaminophen (paracetamol, APAP) to relieve pain; [3] however, to achieve DXM's dissociative effects, the maximum daily therapeutic dose of 4000 mg of APAP is often exceeded, potentially causing acute or chronic liver failure, making abuse and subsequent tolerance of products which ...
Decongestants may improve nasal congestion in sinus infections. Examples are ephedrine, phenylephrine, pseudoephedrine, and oxymetazoline. Fever or pain medication. Examples are paracetamol (acetaminophen) and NSAIDs such as ibuprofen or naproxen.
Guaifenesin is an oral medication used to try to help cough out phlegm from the airways. [1] It is often used in combination with other medications. [1] It is believed to work by making airway secretions more liquid. [1]
Sinusitis, also known as rhinosinusitis, is an inflammation of the mucous membranes that line the sinuses resulting in symptoms that may include production of thick nasal mucus, nasal congestion, facial congestion, facial pain, facial pressure, loss of smell, or fever.