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History of Parkinson's disease. The history of Parkinson's disease expands from 1817, when British apothecary James Parkinson published An Essay on the Shaking Palsy, to modern times. Before Parkinson's descriptions, others had already described features of the disease that would bear his name, while the 20th century greatly improved knowledge ...
For the study, researchers analyzed data from 9,350 people with no previous history of Parkinson’s disease. They discovered that those who had mucosal damage had a 76 percent greater risk of ...
Parkinson's disease (PD) is a complicated neurodegenerative disease that progresses over time and is marked by bradykinesia, tremor, and stiffness. As the condition worsens, some patients may also experience postural instability. [1] Parkinson's disease (PD) is primarily caused by the gradual degeneration of dopaminergic neurons in the region ...
As of 2022, no disease-modifying drugs (drugs that target the causes or damage) are approved for Parkinson's, so this is a major focus of Parkinson's research. [ 270 ] [ 271 ] Active research directions include the search for new animal models of the disease and studies of the potential usefulness of gene therapy , stem cell transplants, and ...
However, the study of genetic forms of Parkinson's can assist scientists in learning more about the non-inherited forms. Several current studies are examining the genetic factors of Parkinson's disease. [17] An example of genetic research is a recent study that investigated the GBA gene as a suspected cause of early-onset Parkinson's. [18]
Alice M. Lazzarini is a scientist, author and researcher on neurogenetic disorders, including Huntington's disease and Parkinson's disease.She is an assistant professor of Neurology at Rutgers Robert Wood Johnson Medical School (RWJMS, previously known as University of Medicine and Dentistry of New Jersey or UMDNJ), where her work helped establish the genetic basis of Parkinson's.
A recent study conducted by scientists from the Icahn School of Medicine at Mount Sinai, NY, uncovers fresh details about the links between Parkinson’s disease and inflammatory bowel disease (IBD).
Parkinson's Disease causes constipation and gastric dysmotility that is severe enough to endanger comfort and even health. [26] A factor in this is the appearance of Lewy bodies and Lewy neurites even before these affect the functioning of the substantia nigra in the neurons in the enteric nervous system that control gut functions.