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The most commonly reported side effects of dutasteride, although rare, include sexual dysfunction and depression. [7] In the largest available study of 6,729 men with BPH, 9% experienced erectile dysfunction (compared to 5.7% treated with a placebo ), 3.3% experienced decreased sex drive (vs 1.6% of placebo), and 1.9% had enlarged breasts (vs 1 ...
In Wikidata. 5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss. They are also sometimes used to treat excess hair growth in women and as a component of hormone therapy for ...
Antiandrogens. Finasteride is used to treat male pattern hair loss. [25] Treatment provides about 30% improvement in hair loss after six months of treatment, and effectiveness only persists as long as the drug is taken. [20] There is no good evidence for its use in women. [14] It may cause gynecomastia, erectile dysfunction and depression.
Common side effects include abdominal pain, gastrointestinal bleeding, nausea, dizziness, headache, and swelling. [7] Serious side effects may include heart disease, stroke, kidney problems, and stomach ulceration. [12] [7] Use is not recommended in the third trimester of pregnancy. [7] It is likely safe during breastfeeding. [12]
Relative to steroidal antiandrogens like cyproterone acetate and spironolactone, bicalutamide has better selectivity in its action, superior efficacy as an antagonist of the androgen receptor, and better tolerability. Bicalutamide also shows a better safety profile than cyproterone acetate. When used as a high-dosage monotherapy, bicalutamide ...
It is a combination of two previously existing medications: dutasteride, brand name Avodart, and tamsulosin, brand name Flomax. It contains 0.5 mg of dutasteride and 0.4 mg of tamsulosin hydrochloride. [2] Jalyn was the result of the CombAT (Combination of Avodart and Tamsulosin) trial of 2008.
Bicalutamide is used primarily in the treatment of early and advanced prostate cancer. [1] It is approved at a dosage of 50 mg/day as a combination therapy with a gonadotropin-releasing hormone analogue (GnRH analogue) or orchiectomy (that is, surgical or medical castration) in the treatment of stage D2 metastatic prostate cancer (mPC), [2] [3] and as a monotherapy at a dosage of 150 mg/day ...
Fox local. Leah Beno. August 25, 2024 at 11:14 PM. MINNEAPOLIS (FOX 9) - Atrial fibrillation is being diagnosed at an alarming rate, but a therapy long used in Europe is now available in the ...