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  2. Multiple system atrophy - Wikipedia

    en.wikipedia.org/wiki/Multiple_system_atrophy

    Levodopa (L-Dopa), a drug used in the treatment of Parkinson's disease, improves parkinsonian symptoms in a small percentage of MSA patients. A recent trial reported that only 1.5% of MSA patients experienced any improvement at all when taking levodopa, their improvement was less than 50%, and even that improvement was a transient effect ...

  3. Primary lateral sclerosis - Wikipedia

    en.wikipedia.org/wiki/Primary_lateral_sclerosis

    Like ALS, diagnosing PLS is a diagnosis of exclusion, as there is no one test that can confirm a diagnosis of PLS. The Pringle Criteria, [11] proposed by Pringle et al., provides a guideline of nine points that, if confirmed, can suggest a diagnosis of PLS. Due to the fact that a person with ALS may initially present with only upper motor ...

  4. Neurodegenerative disease - Wikipedia

    en.wikipedia.org/wiki/Neurodegenerative_disease

    Neurodegenerative diseases include amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple system atrophy, tauopathies, and prion diseases. Neurodegeneration can be found in the brain at many different levels of neuronal circuitry, ranging from molecular to systemic. [4]

  5. Inflammatory demyelinating diseases of the central nervous ...

    en.wikipedia.org/wiki/Inflammatory_demyelinating...

    The current diagnosis criteria for MS do not allow doctors to give an MS diagnosis until a second attack takes place. Therefore, the concept of "clinical MS", for an MS that can be diagnosed, has been developed. Until MS diagnosis has been established, nobody can tell whether the disease one is dealing with is MS. [citation needed]

  6. Synucleinopathy - Wikipedia

    en.wikipedia.org/wiki/Synucleinopathy

    There are three main types of synucleinopathy: Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). [1] Other rare disorders, such as various neuroaxonal dystrophies, also have α-synuclein pathologies. [ 2 ]

  7. ALS has killed multiple people in my family. Now it's coming ...

    www.aol.com/news/als-killed-multiple-people...

    Thank goodness, after my diagnosis, my neurologist at Rutgers took swift action and referred me to Columbia University’s Eleanor and Lou Gehrig ALS Center, where a new treatment called tofersen ...

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