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The bruising appears as a blue discoloration, [1] and is a sign of retroperitoneal hemorrhage, or bleeding behind the peritoneum, which is a lining of the abdominal cavity. Grey Turner's sign takes 24–48 hours to develop, and can predict a severe attack of acute pancreatitis. [2] Grey Turner's sign may be accompanied by Cullen's sign. Both ...
This sign takes 24–48 hours to appear and can predict acute pancreatitis, with mortality rising from 8–10% to 40%. It may be accompanied by Grey Turner's sign [ 3 ] (bruising of the flank), which may then be indicative of pancreatic necrosis with retroperitoneal or intra-abdominal bleeding.
Grey Turner's sign: George Grey Turner: surgery: retroperitoneal hemorrhage: flank ecchymosis Griffith's sign: Alexander Hill Griffith, Scottish Ophthalmologist, Manchester (1858–1937) endocrinology: Graves' ophthalmopathy (needed) lid lag of the lower eyelid on upward eye movement Grisel's syndrome: Pierre Grisel: rheumatology
Grey-Turner's sign (hemorrhagic discoloration of the flanks) or Cullen's sign (hemorrhagic discoloration of the umbilicus) are associated with severe disease. However both signs are rare (occurring in less than 1% of cases of acute pancreatitis) and are not specific nor sensitive for diagnosis of acute pancreatitis. [ 6 ]
Kehr's sign is the occurrence of acute pain in the tip of the shoulder due to the presence of blood or other irritants in the peritoneal cavity when a person is lying down and the legs are elevated. Kehr's sign in the left shoulder is considered a classic symptom of a ruptured spleen .
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The attachment of the fascia to deeper layers confines fluid which may have come from inside the body in certain diseases giving rise to clinical signs such as urethral disruption noticed by Colles and bruising in Cullen's sign or Grey Turner's sign. [4]
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