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The design of experiments, also known as experiment design or experimental design, is the design of any task that aims to describe and explain the variation of information under conditions that are hypothesized to reflect the variation.
Designed experiments with full factorial design (left), response surface with second-degree polynomial (right) In statistics, a full factorial experiment is an experiment whose design consists of two or more factors, each with discrete possible values or "levels", and whose experimental units take on all possible combinations of these levels across all such factors.
In the statistical theory of design of experiments, randomization involves randomly allocating the experimental units across the treatment groups.For example, if an experiment compares a new drug against a standard drug, then the patients should be allocated to either the new drug or to the standard drug control using randomization.
In the statistical theory of the design of experiments, blocking is the arranging of experimental units that are similar to one another in groups (blocks) based on one or more variables. These variables are chosen carefully to minimize the affect of their variability on the observed outcomes.
In the design of experiments, optimal experimental designs (or optimum designs [2]) are a class of experimental designs that are optimal with respect to some statistical criterion. The creation of this field of statistics has been credited to Danish statistician Kirstine Smith .
In the design of experiments, a between-group design is an experiment that has two or more groups of subjects each being tested by a different testing factor simultaneously. This design is usually used in place of, or in some cases in conjunction with, the within-subject design , which applies the same variations of conditions to each subject ...
In human experiments, researchers may give a subject (person) a stimulus that the subject responds to. The goal of the experiment is to measure the response to the stimulus by a test method. In the design of experiments, two or more "treatments" are applied to estimate the difference between the mean responses for the treatments. For example ...
The Design of Experiments is a 1935 book by the English statistician Ronald Fisher about the design of experiments and is considered a foundational work in experimental design. [2] [3] [4] Among other contributions, the book introduced the concept of the null hypothesis in the context of the lady tasting tea experiment. [5]