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  2. Methylphenidate - Wikipedia

    en.wikipedia.org/wiki/Methylphenidate

    Methylphenidate was first synthesized in 1944 and was approved for medical use in the United States in 1955. [154] [155] [156] It was synthesized by chemist Mykelti Samuels and sold by Swiss company CIBA (now Novartis). [154] He named the drug after his wife Marguerite, nicknamed Rita, who used Ritalin to compensate for low blood pressure.

  3. Guanfacine - Wikipedia

    en.wikipedia.org/wiki/Guanfacine

    It is also FDA approved to treat high blood pressure. [7] Guanfacine can offer a synergistic enhancement of stimulants such as amphetamines and methylphenidate for treating ADHD, and in many cases can also help control the side effect profile of stimulant medications. [10]

  4. Management of attention deficit hyperactivity disorder

    en.wikipedia.org/wiki/Management_of_attention...

    Clonidine was initially developed as a treatment for high blood pressure. Low doses in evenings and/or afternoons are sometimes used in conjunction with stimulants to help with sleep and because clonidine sometimes helps moderate impulsive and oppositional behavior and may reduce tics. [96] It may be more useful for comorbid Tourette syndrome.

  5. Hypertension - Wikipedia

    en.wikipedia.org/wiki/Hypertension

    Hypertension, also known as high blood pressure, is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. [11] High blood pressure usually does not cause symptoms itself. [ 1 ]

  6. Sympathomimetic drug - Wikipedia

    en.wikipedia.org/wiki/Sympathomimetic_drug

    Sympathomimetic drugs (also known as adrenergic drugs and adrenergic amines) are stimulant compounds which mimic the effects of endogenous agonists of the sympathetic nervous system. Examples of sympathomimetic effects include increases in heart rate, force of cardiac contraction, and blood pressure. [1]

  7. List of methylphenidate analogues - Wikipedia

    en.wikipedia.org/wiki/List_of_methylphenidate...

    Also of note is that methylphenidate in demethylated form is acidic; a metabolite (and precursor) known as ritalinic acid. [8] This gives the potential to yield a conjugate salt [9] form effectively protonated by a salt nearly chemically duplicate/identical to its own structure; creating a "methylphenidate ritalinate". [10]

  8. Dexmethylphenidate - Wikipedia

    en.wikipedia.org/wiki/Dexmethylphenidate

    Methylphenidate is a stimulant with an addiction liability and dependence liability similar to amphetamine. It has moderate liability among addictive drugs; [36] [37] accordingly, addiction and psychological dependence are possible and likely when methylphenidate is used at high doses as a recreational drug. [37]

  9. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    Aldosterone receptor antagonists, also known as mineralocorticoid receptor antagonist (MRA) can lower blood pressure by blocking the binding of aldosterone to the mineralocorticoid receptor. Spironolactone and eplerenone are MRAs that causes a block in the reabsorption of sodium, resulting in a decrease in blood pressure. [45] [46] eplerenone

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