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Perlia's nucleus, also known as nucleus of Perlia and abbreviated as NP, is a spindle-shaped nucleus located in the mesencephalon, a subdivision of the Edinger-Westphal nucleus [1] [2] situated between the right and left oculomotor nuclei. It is implicated in parasympathetic oculomotor functions, possibly including input to the iris and ciliary.
The Edinger–Westphal nucleus also called the accessory or visceral oculomotor nerve, is one of the two nuclei of the oculomotor nerve (CN III) located in the midbrain. [ 1 ] [ 2 ] [ 3 ] It receives afferents from both pretectal nuclei (which have in turn received afferents from the optic tract ). [ 4 ]
The subparabrachial nucleus (also known as the Kölliker-Fuse nucleus, or diffuse reticular nucleus) regulates the breathing rate. It receives signals from the caudal , cardio-respiratory part of the solitary nucleus and sends signals to the lower medulla oblongata , the spinal cord , the amygdala and the lateral hypothalamus .
A cross section of the lower part of the pons showing the pontine reticular formation labeled as #9. The human reticular formation is composed of almost 100 nuclei and contains many projections into the forebrain, brainstem, and cerebellum, among other regions. [6]
The outlook for someone with lateral medullary syndrome depends upon the size and location of the area of the brain stem damaged by the stroke. [2] Some individuals may see a decrease in their symptoms within weeks or months, while others may be left with significant neurological disabilities for years after the initial symptoms appear. [ 4 ]
Red nucleus: This is a motor nucleus that sends a descending tract to the lower motor neurons. Substantia nigra pars compacta: This is a concentration of neurons in the ventral portion of the midbrain that uses dopamine as its neurotransmitter and is involved in both motor function and emotion. Its dysfunction is implicated in Parkinson's disease.
Mammillary body atrophy is present in several other conditions, such as colloid cysts in the third ventricle, Alzheimer's disease, schizophrenia, heart failure, and sleep apnea. In spite of this the exact function of the mammillary bodies is still not clear.
The zona incerta receives pain input through the spinothalamic tract and this has been shown to control the activity of the pain transmission pathway in the posterior thalamus. [15] Electrical or chemical stimulation of the zona incerta creates limbic-related movements, such as those associated with defense orientation and copulation. [28]