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Postherpetic neuralgia (PHN) is neuropathic pain that occurs due to damage to a peripheral nerve caused by the reactivation of the varicella zoster virus (herpes zoster, also known as shingles). PHN is defined as pain in a dermatomal distribution that lasts for at least 90 days after an outbreak of herpes zoster. [ 1 ]
It is a commonly used medication for the treatment of neuropathic pain caused by diabetic neuropathy, postherpetic neuralgia, and central pain. [11] It is moderately effective: about 30–40% of those given gabapentin for diabetic neuropathy or postherpetic neuralgia have a meaningful benefit. [12]
Neuropathic pain and post-herpetic neuralgia can commonly persist for more than 3 months and a year to 18 months is not uncommon. More than 50% of patients report experiencing post-herpetic neuralgia. [2] Post-herpetic fatigue is also a common long term side effect and may persist for several months to a year or more.
It has been FDA-approved to help control and treat seizures and to diminish a specific type of nerve pain called post-herpetic neuralgia that often follows a shingles' diagnosis.
Medicare’s chronic pain management and treatment coverage ... with postherpetic neuralgia or neuropathic pain associated with diabetic peripheral neuropathy, talk with your doctor about how best ...
Zoster vaccination is used to prevent shingles and its complications, including postherpetic neuralgia. [8] [9] It can be considered a therapeutic vaccine, given that it is used to treat a latent virus that has remained dormant in cells since chicken pox infection earlier in life. [8]